Calcium Phosphate/Demineralized Bone Matrix Performance in a Rabbit Posterolaterial Lumbar Arthrodesis Model

INTRODUCTION: Synthetic calcium phosphate cements (CPC) which mimic the chemical structure of the mineral composition of bone have been well accepted as bone grafting materials due to their consistent osteoconductivity, ease of use, and mechanical properties but are limited in application due to their lack of osteoinductive potential. Demineralized Bone Matrix (DBM) has also found significant acceptance as a bone grafting material but is limited in application due to its lack of mechanical properties and inconsistent performance. An optimized graft material would combine the consistency, mechanical properties and osteoconductivity of calcium phosphate cements with the osteoinductive potential of DBM.